Suitable protein stem cell lines derived from fat cells into the muscles involved in the show than

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Two adipose-derived stem cells show the continuity of the cytoskeleton, indicating that they are together. Under similar conditions in the laboratory, bone marrow-derived stem cells can not be integrated. Adipose-derived stem cells (fat-derived stem cell) has a surprisingly good ideas: Once they are motivated when a hard surface trustee growth, has undergone trustee a remarkable transformation they become mature muscle cells. This is a new study published in the journal Biomaterials. These newly formed myocytes and together remain intact, even if they are extremely hard bone is transferred to a similar surface. These findings trustee lead to the San Diego bioengineering professor at the University of California, Adam Engler trustee and colleagues interest. They believe that these cells may be prompted with a new way to treat muscular dystrophy (Muscular Dystrophy, MD)'s. Engler said diseases such as heart disease, muscular dystrophy or the like, the "muscle began to die, and subjected trustee to the normal process of wound." "The damaged tissue is substantially different from a mechanical point of view healthy tissue, he noted that the transplanted stem cells may be able to replace and repair muscle diseases (diseased tissue), but so far these grafts in muscular dystrophy patients has not been very successful when these transplanted cells thicken and struggling to adapt to their new environment damaged tissue, they tend to pile into hard nodules.
Suitable protein stem cell lines derived from fat cells into the muscles involved in the show than their bone marrow stem cells and other objects on a good 40-50 times. Engler said adipose derived stem cells, these proteins are also more likely to be in the correct order along the "ON expression." These scientists tips of these two cell types and how they are subtle differences between environmental interactions essential for their growth. trustee These fatty liver derived stem cells than bone marrow-derived stem cells seem more complete and test them on a surface in which the "micro-environment (niche)" faster. Choi explained, "they quickly perceive their environment, allowing them to understand the interaction between environmental trustee signals from the cell's growth and guidance." Perhaps most surprising is that the growth of stem cells derived from adipose muscle cells together, never before observed myotubes (myotube) is formed to some extent. Myotubes is a critical step in muscle development, the study also shows that a further forward and is Engler and colleagues previously never observed in the laboratory. When the fusion of muscle cells were transferred to a very hard surface, they remain fused state. Engler said, "These reprogrammed cells mature enough so that they may lead them to split open a new environment signal can not react." trustee
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